Urethral Bulking Agents for the Treatment of SUI

Stress urinary incontinence is losing urine when coughing, laughing, sneezing or exercising. Normally the pelvic floor muscles form a cushion supporting the base of the bladder helping to close the urethra, keeping you continent during increases in abdominal pressure. If they do not, additional cushioning can be created by injecting a urethral bulking agent (UBA) into the area around the urethra.

Most UBAs, currently available, were designed for women with SUI due to intrinsic sphincter deficiency (ISD), which tends to be elderly women with more severe urine loss, women unsuitable for surgery or for whom previous surgery for relief of incontinence has failed. Whilst UBAs have been shown to be effective for this group of women, they have the potential to treat women with mild to moderate SUI who are currently managing their condition conservatively, for example through the use of absorbent pads. This often leads to a decreased quality of life and an increasing financial burden. Many women stop activities, such as sports, that make them leak, which in turn negatively affects their quality of life. Furthermore, the increasing use of absorbent pads and adult diapers has a far reaching environmental and financial impact.

It is clear that there is a large group of women with mild to moderate SUI who may be unsure of what treatment options are available for them. Many feel SUI is inevitable or that the symptoms do not warrant seeking medical advice. As a result many women remain untreated. Yet these are exactly the women who would benefit from a minimally-invasive, quick, safe and effective treatment designed to last.

Urolon represents an opportunity for women especially with mild to moderate SUI

Urolon™ is a bioresorbable urethral bulking agent, which means the product is not permanent.

urolon, urethral bulking agent, UBA, slings, pfmt, pelvic floor muscle training, pads, stress urinary incontinence, SUI