Urethral Injectable Implants for the Treatment of SUI

Stress urinary incontinence is losing urine when coughing, laughing, sneezing or exercising. Normally the pelvic floor muscles form a cushion supporting the base of the bladder helping to close the urethra, keeping you continent during increases in abdominal pressure. If they do not, additional cushioning can be created by injecting a bulk volume (implant) into the area around the urethra.

Most UBAs, currently available, were designed for women with SUI due to intrinsic sphincter deficiency (ISD), which tends to be elderly women with more severe urine loss, women unsuitable for surgery or for whom previous surgery for relief of incontinence has failed. Whilst UBAs have been shown to be effective for this group of women. Most traditional Urethral Bulking Agents (UBAs) currently available were designed for women with SUI due to intrinsic sphincter deficiency (ISD), which tends to be elderly women with more severe urine loss, women unsuitable for surgery or for whom previous surgery for relief of incontinence has failed. Whilst UBAs have been shown to be effective for this group of women, this usually is seen as a last resort option.

It is clear that there is a large group of women with mild to moderate SUI who may be unsure of what treatment options are available for them. Many feel SUI is inevitable or that the symptoms do not warrant seeking medical advice. As a result, many women remain untreated. Yet these are exactly the women who would benefit from a minimally-invasive, quick, safe and effective treatment designed to last.

Urolon represents an unique bioresorbable opportunity, especially for women with mild to moderate SUI

Urolon is a Bioresorbable Urethral Implant, which means the product consists of non-permanent materials that are completely removed from the body. As such, Urolon is uniquely suited to bridge the gap between conservative treatment and more invasive surgical interventions with permanent materials. Urolon should be considered a first-choice treatment option in women with mild-to-moderate SUI, before using products that contain permanent materials, or surgical interventions.

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